CAY10790, CAS 107813-86-5

Formulation: A crystalline solid

Formal Name: 3-(2-quinolinylmethoxy)-benzoic acid

Purity: ≥98%

Formula Markup: C17H13NO3

Formula Weight: 279,3

Shelf life (days): 730

CAS Number: 107813-86-5

Notes: CAY10790 is a cysteinyl leukotriene 1 (CysLT1) receptor antagonist (IC50 = 2.8 µM) and G protein-coupled bile acid receptor 1 (GPBAR1) agonist.{67008} It induces receptor transactivation in HEK293T cells expressing human GPBAR1 (EC50 = 3 µM). CAY10790 (10 µM) reduces TNF-α and IL-1β levels in LPS-stimulated RAW 264.7 cells. It also reduces the proliferation of RAW 264.7 cells induced by leukotriene D4 (LTD4; Item No. 20310).

• SKU: CAY35326-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 35326-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK
• Application: Reinstoffe