Cerestat, CAS 137160-11-3

Formulation: A solid

Formal Name: N-(3-ethylphenyl)-N-methyl-N′-1-naphthalenyl-guanidine, monohydrochloride

Purity: ≥98%

Formula Markup: C20H21N3 • HCl

Formula Weight: 339,9

Shelf life (days): 1460

CAS Number: 137160-11-3

Notes: Cerestat is an NMDA receptor antagonist (IC50 = 36 nM).{52616} It is selective for the NMDA receptor over sigma receptors (IC50 = 2,540 nM). Cerestat (1 mg/kg) reduces infarct volume and the number of steps and errors in a foot fault test in a rat model of stroke induced by middle cerebral artery occlusion.{52617} It also reduces cortical and striatal neuronal necrosis in a rat model of temporary focal ischemia when administered at a dose of 1.13 mg/kg.{52618}

• SKU: CAY30966-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 30966-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK