Formulation: A solid
Formal Name: L-tyrosyl-L-phenylalanyl-L-prolylglycyl-L-glutaminyl-L-phenylalanyl-L-alanyl-L-phenylalanyl-L-serine, acetate
Purity: ≥95%
Formula Markup: C54H66N10O13 • XC2H4O2
Formula Weight: 1063,2
Shelf life (days): 1460
Notes: Chemerin-9 is a peptide agonist of chemokine-like receptor 1 (CMKLR1) and CMKLR2, also known as chemerin receptor 1 (chemerin1) and chemerin2, respectively.{17560} It is composed of nine C-terminal amino acids of the endogenous human protein chemerin, a chemotactic protein and adipokine involved in the early immune response and energy homeostasis.{65323} Chemerin-9 binds to CMKLR1 and CMKLR2 (IC50s = 1.9 and 2.3 nM, respectively, in a radioligand binding assay) and induces calcium mobilization in HEK293T cells expressing either CMKLR1 or CMKLR2 and the G protein Gα15 when used at a concentration of 1 µM.{65322}
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