Coclaurine, CAS 486-39-5

Formulation: A solid

Formal Name: (1S)-1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-7-isoquinolinol

Purity: ≥98%

Formula Markup: C17H19NO3

Formula Weight: 285,3

Shelf life (days): 1460

CAS Number: 486-39-5

Notes: Coclaurine is a benzylisoquinoline alkaloid that has been found in T. quinquenervia and has nicotinic acetylcholine receptor (nAChR) inhibitory and insecticidal activities.{62670,62671} It inhibits ACh-induced currents in Xenopus oocytes expressing human α4β2 or α4β4 subunit-containing nAChRs (IC50s = 49 and 18 µM, respectively).{62670} Coclaurine induces mortality in D. melanogaster and C. pomonella larvae (LD50s = 78.2 and 35.4 µg/ml, respectively).{62671}

• SKU: CAY35716-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 35716-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK
• Application: Reinstoffe