Colupulone, CAS 468-27-9

Formulation: A solid

Formal Name: 3,5-dihydroxy-2,6,6-tris(3-methyl-2-buten-1-yl)-4-(2-methyl-1-oxopropyl)-2,4-cyclohexadien-1-one

Purity: ≥95% (mixture of isomers)

Formula Markup: C25H36O4

Formula Weight: 400,6

Shelf life (days): 1460

CAS Number: 468-27-9

Notes: Colupulone is a β-acid that has been found in H. lupulus and has diverse biological activities.{58789,58790,58791} It activates the pregnane X receptor (PXR) in a reporter assay when used at concentrations of 1, 3, and 10 µM.{58789} Dietary administration of colupulone (0.18% w/w) induces hepatic cytochrome P450 (CYP) isoform 3A (CYP3A) activity in mice.{58790} It also decreases serum glucose levels in non-diabetic mice and increases serum glucose levels in db/db mice.{58791}

• SKU: CAY34048-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 34048-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK