Compound 48/80 (hydrochloride)

Formulation: A solid

Purity: ≥95% (mixture of polymers)

Formula Markup: C32H45N3O3 • XHCl (for trimer)

Formula Weight: 519,7

Shelf life (days): 1460

Notes: Compound 48/80 is a condensation product of N-methyl-p-methoxyphenethylamine with formaldehyde that causes histamine degranulation from mast cells.{36028} Compound 48/80 also inhibits human platelet aggregation through suppression of calmodulin (CaM) (IC50 = 0.41 μg/ml for CaM-dependent Ca2+-transporter ATPase activity) and phospholipase C (IC50s = 2.1 and 5.0 μg/ml for cytosolic and particulate phosphatidylinositol-specific activities, respectively).{36029,36030}

• SKU: CAY22173-100
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 22173-100
• Green Labware: No
• Package Unit: 100 mg
• Quantity Unit: STK