Formulation: A solid
Formal Name: 3-[3-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-4-hydroxyphenyl]-7-hydroxy-4H-1-benzopyran-4-one
Purity: ≥98%
Formula Markup: C25H26O4
Formula Weight: 390,5
Shelf life (days): 1460
CAS Number: 775351-88-7
Notes: Corylifol A is a flavonoid that has been found in P. corylifolia and has diverse biological activities.{63218,63219,31782,63220} It inhibits the activity of carboxylesterase 2 (CES2; Ki = 0.62 µM for the human enzyme), as well as induces estrogen receptor α (ERα) and ERβ transcriptional activation in reporter assays using HeLa cells when used at concentrations ranging from 0.1 to 10 µM.{63219,31782} Corylifol A is cytotoxic to (IC50 = 13.5 µg/ml), and inhibits IL-6-induced STAT3 promoter activity in (IC50 = 0.81 µM in a reporter assay), Hep3B hepatocellular carcinoma cells.{63220,63218}