CU-CPT4a, CAS 1279713-77-7

Formulation: A solid

Formal Name: N-[(3-chloro-6-fluorobenzo[b]thien-2-yl)carbonyl]-D-phenylalanine

Purity: ≥98%

Formula Markup: C18H13ClFNO3S

Formula Weight: 377,8

Shelf life (days): 1460

CAS Number: 1279713-77-7

Notes: CU-CPT4a is a toll-like receptor 3 (TLR3) antagonist (IC50 = 3.44 µM).{36228} It is selective for TLR3 over TLR4, TLR2/6, TLR1/2, and TLR7 at 27 µM. CU-CPT4a inhibits dsRNA binding to TLR3 with a Ki value of 2.96 µM in a fluorescence anisotropy assay. It decreases poly(I:C)-induced production of TNF-α and IL-1β in RAW 264.7 cells when used at a concentration of 27 µM.

• SKU: CAY30951-500
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 30951-500
• Green Labware: No
• Package Unit: 500 µg
• Quantity Unit: STK