CXCR2-IN-1, CAS 1873376-49-8

Formulation: A solid

Formal Name: N-(2-chloro-3-fluorophenyl)-N′-[4-chloro-2-hydroxy-3-[(1-methyl-4-piperidinyl)sulfonyl]phenyl]-urea

Purity: ≥98%

Formula Markup: C19H20Cl2FN3O4S

Formula Weight: 476,3

Shelf life (days): 1460

CAS Number: 1873376-49-8

Notes: CXCR2-IN-1 is a chemokine (C-X-C motif) receptor 2 (CXCR2) antagonist (IC50 = 0.501 nM in a reporter assay).{50113} It inhibits chemotaxis of isolated human neutrophils induced by chemokine (C-X-C motif) ligand 1 (CXCL1; IC50 = 79.4 nM). In vivo, CXCR2-IN-1 (100 mg/kg) inhibits forebrain lesion formation in a mouse model of cuprizone-induced demyelination.

• SKU: CAY28426-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 28426-5
• Package Unit: 5 mg
• Quantity Unit: STK