Formulation: A white powder
Formal Name: 5-(N-methyl-D-valine)-cyclosporin A
Purity: ≥95%
Formula Markup: C62H111N11O12
Formula Weight: 1202,6
Shelf life (days): 1460
CAS Number: 83602-39-5
Notes: Cyclosporin H is a natural cyclic undecapeptide that selectively antagonizes the formyl peptide receptor at concentrations ranging from 0.1 to 10 µM.{28067,28068,28069} Unlike cyclosporin A (Item No. 12088), cyclosporin H does not bind cyclophilin to evoke an immunosuppressant response.{28070} Cyclosporin H has been reported to inhibit phorbol ester-mediated effects in mouse skin and block calcium/calmodulin-dependent EF-2 phosphorylation in vitro.{28071}