DADLE, CAS 63631-40-3

Formulation: A crystalline solid

Formal Name: L-tyrosyl-D-alanylglycyl-L-phenylalanyl-D-leucine

Purity: ≥98%

Formula Markup: C29H39N5O7

Formula Weight: 569,7

Shelf life (days): 1460

CAS Number: 63631-40-3

Notes: DADLE is a peptide agonist of δ-opioid receptors (Ki = 2.06 nM in a radioligand binding assay).{37712} It is selective for δ-opioid over κ-opioid receptors (Ki = 16,000 nM) but also agonizes μ-opioid receptors (Ki = 13.8 nM). DADLE inhibits electrically induced contractions in guinea pig myenteric plexus and mouse and rat vas deferens (IC50s = 8.9, 0.73, and 134 nM, respectively). It induces analgesia in the tail-flick and hot plate tests in mice (ED50s = 0.03 and 0.027 nmol per animal, i.c.v.).{52196}

• SKU: CAY28928-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 28928-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK