Darodipine, CAS 72803-02-2

Formulation: A solid

Formal Name: 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid, 3,5-diethyl ester

Purity: ≥95%

Formula Markup: C19H21N3O5

Formula Weight: 371,4

Shelf life (days): 1460

CAS Number: 72803-02-2

Notes: Darodipine is a calcium channel inhibitor.{68897} It selectively inhibits calcium-induced contractions of isolated rabbit aorta (pD2 = 8.8) over norepinephrine-, serotonin-, or angiotensin II-induced contractions at 10 µM. In vivo, continuous infusion of darodipine (2 µg/kg per minute) increases cerebral tissue oxygenation in a cat model of focal ischemia induced by cerebral artery occlusion (CAO).{68898} Darodipine (5 mg/kg) reduces mean arterial blood pressure and increases arterial luminal area in spontaneously hypertensive rats (SHRs).{68899}

• SKU: CAY41667-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 41667-1
• Package Unit: 1 mg
• Quantity Unit: STK