DC260126, CAS 346692-04-4

Formulation: A crystalline solid

Formal Name: N-(4-butylphenyl)-4-fluoro-benzenesulfonamide

Purity: ≥98%

Formula Markup: C16H18FNO2S

Formula Weight: 307,4

Shelf life (days): 1460

CAS Number: 346692-04-4

Notes: DC260126 is a free fatty acid receptor 1 (FFAR1/GPR40) antagonist that inhibits GPR40-mediated Ca2+ elevations stimulated by linoleic, oleic, palmitoleic, and lauric acid (Item Nos. 90150, 90260, 10009871, and 10006626, respectively) with IC50 values of 6.28, 5.96, 7.07, and 4.58 µM, respectively.{31470} At 10 mg/kg, it has been shown to inhibit glucose-stimulated insulin secretion, to reduce blood insulin levels, to improve insulin sensitivity, and to decrease the rate of pancreatic β-cell apoptosis in obese diabetic db/db mice.{31471}

• SKU: CAY19388-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 19388-50
• Package Unit: 50 mg
• Quantity Unit: STK
• Application: Reinstoffe