(Des-Arg9)-Bradykinin, CAS 15958-92-6

(Des-Arg9)-Bradykinin, CAS 15958-92-6
SKU
CAY31136-25
Packaging Unit
25 mg
Manufacturer
Cayman Chemical

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Formulation: A crystalline solid

Formal Name: 1-8-bradykinin

Purity: ≥98%

Formula Markup: C44H61N11O10

Formula Weight: 904

Shelf life (days): 1460

CAS Number: 15958-92-6

Notes: (Des-Arg9)-Bradykinin is an active metabolite of the endogenous vasodilator bradykinin (Item No. 37408) and a peptide agonist of the bradykinin B1 receptor.{49599,59178} It binds to bradykinin B1 and B2 receptors (Kis = 1.93 and 8.1 µM, respectively).{49601} (Des-Arg9)-Bradykinin is formed via carboxypeptidase-mediated cleavage of the bradykinin C-terminal arginine residue in plasma and tissues.{59178} It induces relaxation of precontracted isolated endothelium-denuded dog renal artery strips (pD2 = 8.6).{49603} (Des-Arg9)-Bradykinin decreases blood pressure in LPS-treated rabbits in a dose-dependent manner.{49600}
More Information
SKU CAY31136-25
Manufacturer Cayman Chemical
Manufacturer SKU 31136-25
Green Labware No
Package Unit 25 mg
Quantity Unit STK
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