Desethoxy Quetiapine (hydrochloride), CAS 329218-14-6

Formulation: A solid

Formal Name: 4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazineethanol, dihydrochloride

Purity: ≥95%

Formula Markup: C19H21N3OS • 2HCl

Formula Weight: 412,4

Shelf life (days): 1460

CAS Number: 329218-14-6

Notes: Desethoxy quetiapine is an active metabolite of the atypical antipsychotic quetiapine (Item No. 14152).{57986} It is formed from quetiapine primarily by the cytochrome P450 (CYP) isoform CYP3A5 and binds to dopamine D2 receptors (IC50 = 1,330 nM).{57987,57986} Desethoxy quetiapine (20 and 40 mg/kg) reduces climbing induced by the dopamine receptor agonist apomorphine in mice. It also improves apomorphine-induced swimming deficits in mice.{57986}

• SKU: CAY35410-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 35410-50
• Green Labware: No
• Package Unit: 50 mg
• Quantity Unit: STK
• Application: Reinstoffe