Formulation: A solid
Formal Name: 9-fluoro-11β,17,21-trihydroxy-16α-methyl-pregna-1,4-diene-3,20-dione-4,6,21,21-d4
Purity: ≥99% deuterated forms (d1-d4)
Formula Markup: C22H25D4FO5
Formula Weight: 396,5
Shelf life (days): 1460
CAS Number: 2483831-63-4
Notes: Dexamethasone-d4 is intended for use as an internal standard for the quantification of dexamethasone (Item No. 11015) by GC- or LC-MS. Dexamethasone is a synthetic glucocorticoid that binds the human glucocorticoid receptor with a higher affinity than a natural ligand, cortisol (Kd = 5 nM versus 17 nM, respectively).{20150} Through receptor activation, dexamethasone has both transactivating and transrepressing effects on gene expression, producing, in general, anti-inflammatory results.{20149}