diABZI STING Agonist 3, CAS 2138299-29-1

Formulation: A solid

Formal Name: 1-[(2E)-4-[5-(aminocarbonyl)-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-1H-benzimidazol-1-yl]-2-buten-1-yl]-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-7-(3-hydroxypropoxy)-1H-benzimidazole-5-carboxamide

Purity: ≥98%

Formula Markup: C37H42N12O6

Formula Weight: 750,8

Shelf life (days): 1460

CAS Number: 2138299-29-1

Notes: diABZI STING agonist 3 is an agonist of stimulator of interferon genes (STING).{57650} It binds to STING (IC50 = 0.32 nM in a FRET assay) and induces STING transcriptional activity in a reporter assay (EC50 = 31.62 nM). diABZI STING agonist 3 increases protein levels of Nod-like receptor protein 3 (NLRP3), IL-1β, and IL-18, but not cGAS or mtDNA, in macrophages.{57649}

• SKU: CAY34082-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 34082-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK