Difelikefalin (trifluoroacetate salt), CAS 2767426-81-1

Formulation: A solid

Formal Name: N1-(D-phenylalanyl-D-phenylalanyl-D-leucyl-D-lysyl)-4-amino-4-piperidinecarboxylic acid, trifluoroacetate salt

Purity: ≥98%

Formula Markup: C36H53N7O6 • XCF3COOH

Formula Weight: 679,9

Shelf life (days): 1460

CAS Number: 2767426-81-1

Notes: Difelikefalin is a κ-opioid receptor (KOR) agonist.{62330} It activates KOR in HEK293 cells expressing the human receptor (EC50 = 0.16 nM in a transactivation assay) and inhibits forskolin-induced cAMP production in R1.G1 mouse thyoma cells (EC50 = 0.048 nM). Difelikefalin is selective for KOR over the μ-opioid receptor (MOR; EC50 = >1 µM in a transactivation assay). It reduces acetic acid-induced writhing, as well as scratching behavior induced by the KOR antagonist GNTI, in mice (ED50s = 0.07 and 0.05 mg/kg, respectively).

• SKU: CAY34542-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 34542-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK