Dimaprit (hydrochloride), CAS 23256-33-9

Formulation: A crystalline solid

Formal Name: carbamimidothioic acid, 3-(dimethylamino)propyl ester, dihydrochloride

Purity: ≥95%

Formula Markup: C6H15N3S • 2HCl

Formula Weight: 234,2

Shelf life (days): 1460

CAS Number: 23256-33-9

Notes: Dimaprit is a histamine H2 receptor agonist with a Ki value of 44 µM in guinea pig right atrium.{46616,46612} It is selective for histamine H2 over H1 and H3 receptors with relative potencies of 71, A. suum extract, which is not affected by pretreatment with mepyramine (Item No. 20978), an H1 receptor inverse agonist, or cimetidine (Item No. 18743), an H2 receptor antagonist.{46613} It stimulates gastric acid secretion in vivo in anaesthetized rats and cats with relative potencies of 19.5 and approximately 400 to 500, respectively, compared to histamine.{46614} Dimaprit inhibits 2-(2-pyridyl)ethylamine-induced bronchoconstriction in guinea pigs in a dose-dependent manner.{46615}

• SKU: CAY29418-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 29418-50
• Green Labware: No
• Package Unit: 50 mg
• Quantity Unit: STK