E4CPG, CAS 170846-89-6

Formulation: A solid

Formal Name: α-amino-4-carboxy-α-ethyl-benzeneacetic acid

Purity: ≥98%

Formula Markup: C11H13NO4

Formula Weight: 223,2

Shelf life (days): 1460

CAS Number: 170846-89-6

Notes: E4CPG is an antagonist of metabotropic glutamate receptor 1 (mGluR1) and mGluR2.{64619} It is selective for mGluR1 and mGluR2 over mGluR6 at 1 mM. E4CPG (1 mM) inhibits L-glutamate-induced increases in inositol phosphate (InsP) levels in CHO cells expressing mGluR1 and prevents forskolin-induced decreases in cAMP levels in CHO cells expressing mGluR2. In vivo, intraplantar administration of E4CPG (1-10 nmol/paw) reduces glutamate-induced paw licking in a mouse model of nociceptive pain.{64620}

• SKU: CAY36667-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 36667-50
• Package Unit: 50 mg
• Quantity Unit: STK
• Application: Reinstoffe