Eptifibatide (acetate), CAS 881997-86-0

Formulation: A crystalline solid

Formal Name: N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide, cyclic (1→6)-disulfide

Purity: ≥95%

Formula Markup: C35H49N11O9S2

Formula Weight: 832

Shelf life (days): 1460

CAS Number: 188627-80-7

Notes: Eptifibatide is a potent glycoprotein IIb/IIIa antagonist (GPIIb/IIIa; Kd = 120 nM) that inhibits platelet aggregation.{38053,38054} Eptifibatide prevents binding of the adhesion proteins fibrinogen and von Willebrand factor to GPIIb/IIIa on the surface of activated platelets to prevent aggregation and thrombus formation.{38055} It inhibits ADP-induced citrated blood aggregation (IC50 = 0.11-0.22 μg/ml) in vitro and in vivo (IC50 = 52 μg/ml in porcine plasma).{38053,38056} Formulations containing eptifibatide have been used to reduce risk of thrombolysis in myocardial infarction in patients undergoing percutaneous coronary intervention.{38057}

• SKU: CAY21578-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 21578-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK