Formulation: A solid
Formal Name: 4-hydroxy-benzoic acid, ethyl ester
Purity: ≥98%
Formula Markup: C9H10O3
Formula Weight: 166,2
Shelf life (days): 1460
CAS Number: 120-47-8
Notes: Ethylparaben is a paraben that has been found in A. bracteatus and has diverse biological activities.{67164,67165,67166,65415} It selectively induces activation of estrogen receptor β (ERβ) over ERα in yeast two-hybrid assays (EC50s = 1.86 and 38.2 µM, respectively). Ethylparaben inhibits carbonic anhydrase I (CAI), CAII, CAVII, CAIX, CAXII, and CAXIV (IC50s = 7.9, 4.8, 8.7, 8.2, 8.6, and 7.7 µM, respectively, for the human enzymes).{67165} It is active against several strains of P. stutzeri and P. aeruginosa (MICs = 400-1,000 µg/ml).{67166} Ethylparaben (0.01 and 0.1%) is cytotoxic to immortalized human meibomian gland epithelial cells.{65415} It has been found in influent and effluent wastewater.{68107} Formulations containing ethylparaben have been used as preservatives in cosmetics, food, and pharmaceuticals.
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