Exendin-3 (9-39) amide, CAS 133514-43-9

Formulation: A crystalline solid

Purity: ≥95%

Formula Markup: C149H234N40O47S

Formula Weight: 3369,8

Shelf life (days): 1460

CAS Number: 133514-43-9

Notes: Exendin-3 (9-39) amide is a truncated form of the exendin-4 (48-86) amide (Item No. 11096) peptide that acts as a potent competitive antagonist for the glucagon-like peptide 1 receptor (GLP-1R; Kd = 1.7 nM in CHL cells transfected with cloned human GLP-1).{27504} It inhibits exendin-3-induced increases in cAMP levels in guinea pig pancreas cells (IC50 = 20 nM).{34476} Exendin-3 (9-39) amide administration in the hypothalamus (10 and 100 µg, i.c.v.) reverses GLP-1 inhibition of feeding behavior in rats.{34477}

• SKU: CAY19890-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 19890-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK
• Application: Reinstoffe