Formulation: A solution in methanol:ammonium hydroxide (70:30)
Formal Name: P-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl] ester-diphosphoric acid, triammonium salt
Purity: ≥95%
Formula Markup: C15H25O7P2 • 3NH4
Formula Weight: 433,4
Shelf life (days): 730
CAS Number: 116057-57-9
Notes: Farnesyl pyrophosphate is an intermediate in the HMG-CoA reductase pathway and used in the biosynthesis of terpenes, terpenoids, and sterols.{8343} It also serves as a donor in post-translational isoprenylation of proteins.{24323} FPP has been identified as an antagonist of P2Y12 receptors (IC50 = 45 μM), attenuating platelet aggregation.{24324} It has also been shown to regulate adipocyte function as an endogenous PPARγ agonist.{24326} Additionally, because of a flexible hydrocarbon chain that enables different conformations, FPP is a promiscuous ligand for a subset of nuclear receptors.{24325}
English
Deutsch
