Fedotozine (tartrate), CAS 133267-27-3

Formulation: A solid

Formal Name: (R)-α-ethyl-N,N-dimethyl-α-[[(3,4,5-trimethoxyphenyl)methoxy]methyl]-benzenemethanamine, [S-(R*,R*)]-2,3-dihydroxybutanedioate

Purity: ≥95%

Formula Markup: C22H31NO4 • C4H6O6

Formula Weight: 523,6

Shelf life (days): 1460

CAS Number: 133267-27-3

Notes: Fedotozine is a κ-opioid receptor agonist.{68758} It binds to κ-opioid receptors in mouse brain membranes (Ki = 0.16 nM). In vivo, fedotozine (10 mg/kg) reduces gastric extension-induced increases in mean arterial pressure (MAP), a marker for hyperalgesia, in a rat model of duodenal acidification-induced gastric hypersensitivity.{68759} It also prevents colonic distension-induced inhibition of gastric motility and emptying in dogs when administered at a dose of 50 µg/kg.{68760}

• SKU: CAY22189-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 22189-5
• Package Unit: 5 mg
• Quantity Unit: STK