Formulation: A solid
Formal Name: 2-methyl-propanoic acid, 2-[(1R)-3-[bis(1-methylethyl)amino]-1-phenylpropyl]-4-(hydroxymethyl)phenyl ester, (2E)-2-butenedioate
Purity: ≥98%
Formula Markup: C26H37NO3 • C4H4O4
Formula Weight: 527,7
Shelf life (days): 1460
CAS Number: 286930-03-8
Notes: Fesoterodine is an antagonist of muscarinic acetylcholine receptors (Kis = 15.8, 11.2, 12.6, 22.4, and 25.1 nM for human M1-5, respectively).{41347} In vivo, fesoterodine (0.01 mg/kg, i.v.) reduces micturition pressure and increases bladder capacity and intercontraction interval (ICI) in conscious female rats. Fesoterodine also reduces intermicturition pressure and prevents bladder overactivity in a rat model of spinal cord injury-induced overactive bladder.{41348}