Fluocinolone acetonide, CAS 67-73-2

Fluocinolone acetonide, CAS 67-73-2
SKU
CAY23027-500
Packaging Unit
500 mg
Manufacturer
Cayman Chemical

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Formulation: A crystalline solid

Formal Name: 6α,9-difluoro-11β,21-dihydroxy-16α,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione

Purity: ≥98%

Formula Markup: C24H30F2O6

Formula Weight: 452,5

Shelf life (days): 1460

CAS Number: 67-73-2

Notes: Fluocinolone acetonide is a synthetic fluorinated corticosteroid that acts as a glucocorticoid receptor agonist (IC50 = 2.0 nM in a radioligand binding assay).{39366} It increases transcriptional activity of the glucocorticoid receptor in HeLa cells (EC50 = 0.7 nM). It inhibits VEGF secretion in a dose-dependent manner and decreases TNF-α-induced angiogenesis in a chick chorioallantoic membrane assay.{39365} Formulations containing fluocinolone acetonide have been used for the treatment of various skin, eye, ear, and nose conditions to reduce inflammation.
More Information
SKU CAY23027-500
Manufacturer Cayman Chemical
Manufacturer SKU 23027-500
Green Labware No
Package Unit 500 mg
Quantity Unit STK
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