Formulation: A crystalline solid
Formal Name: 4-amino-5-chloro-N-[1-[(4-fluorophenyl)methyl]-4-piperidinyl]-2-methoxy-benzamide
Purity: ≥98%
Formula Markup: C20H23ClFN3O2
Formula Weight: 391,9
Shelf life (days): 1460
CAS Number: 154540-49-5
Notes: Fluoroclebopride is a benzamide analog that is used in positron emission tomography (PET) applications.{36209,36205} It binds reversibly to dopamine receptors (Kis = 0.95, 5.7, 5.46, and 144 nM for D2-like, D2(long), D3, and D4 receptors, respectively, in radioligand binding assays).{36208} It is selective for these receptors over D1, serotonin 5-HT2, and α2-adrenergic receptors (Kis = >10,000, 283, and 1,300 nM, respectively).{36206,36207} A fluorine-18 moiety has been used to label this compound for use as a probe for studying D2/D3 receptor availability via PET in various monkey models.{36209,36205}
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