Formulation: A solid
Formal Name: 3,8-dihydroxy-4,9-dimethyl-1,6-bis[(1Z)-1-methyl-1-propen-1-yl]-11H-dibenzo[b,e][1,4]dioxepin-11-one
Purity: ≥95%
Formula Markup: C23H24O5
Formula Weight: 380,4
Shelf life (days): 1460
CAS Number: 139959-71-0
Notes: Folipastatin is a fungal metabolite produced by A. unguis and an inhibitor of phospholipase A2 (PLA2; IC50 = 39 μM).{38997} It inhibits release of arachidonic acid (Item Nos. 90010 / 10006607) from rat polymorphonuclear leukocytes (IC50 = 24 μM). Folipistatin also inhibits radioligand binding to L-type calcium channels in porcine heart membranes (IC50 = 0.39 μM) but has no effect on contraction of taenia (IC50 = >100 μM).