Formulation: A solid
Formal Name: 2,2',2''-[1,2,3-benzenetriyltris(oxy)]tris[N,N,N-triethyl]-ethanaminium, triiodide
Purity: ≥95%
Formula Markup: C30H60N3O3 • 3I
Formula Weight: 891,5
Shelf life (days): 1460
CAS Number: 65-29-2
Notes: Gallamine is an allosteric modulator of muscarinic acetylcholine receptors.{45058} It slows the dissociation of the muscarinic antagonist [3H]NMS from M1-M5 muscarinic receptors, with the highest potency for M2 receptors. Gallamine is cardioselective, inhibiting [3H]NMS binding in rat heart tissue homogenates more potently than in other tissues (IC50s = 0.8 and 3-30 µM, respectively).{45059} Formulations containing gallamine have previously been used as neuromuscular blockers during surgery.