Formulation: A solid
Formal Name: 26,27-dihydroxy-lanosta-7,9(11),24-trien-3-one
Purity: ≥98%
Formula Markup: C30H46O3
Formula Weight: 454,7
Shelf life (days): 1460
CAS Number: 114567-47-4
Notes: Ganoderiol F is a triterpenoid that has been found in G. lucidum and has diverse biological activities.{65874,65875,65876,48842} It reduces LPS-induced nitric oxide (NO) production and increases heme oxygenase-1 (HO-1) levels in RAW 264.7 cells when used at a concentration of 50 µM.{65874} Ganoderiol F is a farnesoid X receptor (FXR) agonist, inducing reporter gene expression in HEK293 cells expressing the recombinant human receptor (EC50 = 5 µM).{65875} It inhibits complement-dependent hemolysis of isolated sheep red blood cells (IC50 = 48 µM).{65876} Ganoderiol F also reduces HIV-1 viral proliferation in MT-4 cells (IC50 = 7.8 µg/ml).{48842}
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