Glucagon Receptor Antagonist 4, CAS 1393124-08-7

Formulation: A crystalline solid

Formal Name: N-[4-[(1S)-1-[3,5-dimethyl-4-[4-(trifluoromethyl)-1H-pyrazol-1-yl]phenoxy]butyl]benzoyl]-β-alanine

Purity: ≥98%

Formula Markup: C26H28F3N3O4

Formula Weight: 503,5

Shelf life (days): 1460

CAS Number: 1393124-08-7

Notes: Glucagon receptor antagonist 4 is an antagonist of the glucagon receptor (GCGR; Ki = 14 nM for the human recombinant receptor).{42993} It is greater than 230-fold selective for GCGR over the glucagon-like peptide 1 (GLP-1) receptor, as well as a panel of 69 receptors, ion channels, uptake sites, and enzymes at 10 µM. Glucagon receptor antagonist 4 prevents glucagon-induced increases in glucose levels in rat blood when administered at doses of 7.5 and 75 mg/kg.

• SKU: CAY22164-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 22164-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK