Glucagon Receptor Antagonist I, CAS 438618-32-7

Formulation: A crystalline solid

Formal Name: N-[3-cyano-6-(1,1-dimethylpropyl)-4,5,6,7-tetrahydrobenzo[b]thien-2-yl]-2-ethyl-butanamide

Purity: ≥99%

Formula Markup: C20H30N2OS

Formula Weight: 346,5

Shelf life (days): 730

CAS Number: 438618-32-7

Notes: Glucagon receptor antagonist I is a competitive antagonist of the glucagon receptor (GCGR; IC50 = 181 nM).{33305} It blocks glucagon-induced glycogenolysis in primary human hepatocytes and isolated liver.{33305} Glucagon receptor antagonist I, at 50 mg/kg, reduces the increase in glucose levels observed after intraperitoneal administration of glucagon in humanized mice.{33305} Glucagon receptor antagonist inactive control (Item No. 21188) does not prevent glucagon-mediated actions.{33305}

• SKU: CAY21223-500
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 21223-500
• Green Labware: No
• Package Unit: 500 µg
• Quantity Unit: STK