GR89696 (fumarate), CAS 126766-32-3

Formulation: A solid

Formal Name: 4-[2-(3,4-dichlorophenyl)acetyl]-3-(1-pyrrolidinylmethyl)-1-piperazinecarboxylic acid, methyl ester, (2E)-2-butenedioate

Purity: ≥98%

Formula Markup: C19H25Cl2N3O3 • C4H4O4

Formula Weight: 530,4

Shelf life (days): 1460

CAS Number: 126766-32-3

Notes: GR89696 is a κ-opioid receptor agonist.{65993} It inhibits twitch responses in isolated mouse vas deferens (IC50 = 0.12 nM), an effect that can be reversed by the κ-opioid receptor antagonist norbinaltorphimine (nor-BNI). In vivo, GR89696 reduces acetylcholine-induced writhing in mice (ED50 = 0.0005 mg/kg). It reduces hippocampal neuronal loss in a gerbil model of cerebral ischemia induced by bilateral carotid artery occlusion when administered at doses of 10 and 30 mg/kg.{65994}

• SKU: CAY40145-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 40145-5
• Package Unit: 5 mg
• Quantity Unit: STK