GRA Ex-25, CAS 307983-31-9

Formulation: A crystalline solid

Formal Name: N-[4-[[[trans-4-(1,1-dimethylethyl)cyclohexyl][[[4-(trifluoromethoxy)phenyl]amino]carbonyl]amino]methyl]benzoyl]-β-alanine

Purity: ≥98%

Formula Markup: C29H36F3N3O5

Formula Weight: 563,6

Shelf life (days): 1460

CAS Number: 307983-31-9

Notes: GRA Ex-25 is a glucagon receptor (GCGR) antagonist (IC50s = 55 and 56 nM for the human and rat receptors, respectively).{49499} It inhibits adenylate cyclase activity induced by glucagon (Item No. 24204) with a Ki value of 254 nM.{49500} GRA Ex-25 (3 mg/kg, i.v.) reduces glucagon-induced increases in blood glucose levels in rats.{49499}

• SKU: CAY29727-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 29727-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK