H-151, CAS 941987-60-6

Formulation: A crystalline solid

Formal Name: N-(4-ethylphenyl)-N'-1H-indol-3-yl-urea

Purity: ≥98%

Formula Markup: C17H17N3O

Formula Weight: 279,3

Shelf life (days): 730

CAS Number: 941987-60-6

Notes: H-151 is an inhibitor of stimulator of interferon genes (STING).{35390} It forms an adduct with mouse STING in serum and acts in an irreversible manner. It inhibits the type I interferon (IFN) response and reduces the phosphorylation of TBK1 and palmitoylation of human STING (hsSTING) in vitro. It also reduces increases in mouse serum levels of IFN-β and IL-6 induced by the STING agonist 10-carboxymethyl-9-acridanone (CMA).

• SKU: CAY25857-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 25857-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK