Formulation: A crystalline solid
Formal Name: rel-4,4′-[(1R,2S)-1,2-diethyl-1,2-ethanediyl]bis-phenol
Purity: ≥98%
Formula Markup: C18H22O2
Formula Weight: 270,4
Shelf life (days): 1460
CAS Number: 84-16-2
Notes: Hexestrol is a synthetic non-steroidal estrogen receptor ligand that binds to estrogen receptor α (ERα) and ERβ (Kis = 0.06 and 0.06 nM for the human and rat receptors, respectively).{23592} It inhibits rat liver microsomal and ox brain phospholipid liposomal lipid peroxidation (IC50s = 1.5 and 2.75 μM, respectively).{45569} It also inhibits porcine microtubule assembly and induces disassembly of preformed microtubules when used at concentrations of 50 and 100 μM, respectively, in a cell-free assay.{45571} Hexestrol (25 mg/animal) induces kidney tumors in male Syrian hamsters.{45570}