Hydroxy Pioglitazone, CAS 146062-44-4

Formulation: A solid

Formal Name: 5-[[4-[2-[5-(1-hydroxyethyl)-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedione

Purity: ≥95%

Formula Markup: C19H20N2O4S

Formula Weight: 372,4

Shelf life (days): 1460

CAS Number: 146062-44-4

Notes: Hydroxy pioglitazone is a major metabolite of the peroxisome proliferator-activated receptor γ (PPARγ) agonist pioglitazone (Item Nos. 71745 / 22263 / 10028).{48274} It is formed from pioglitazone by the cytochrome P450 (CYP) isoform CYP2C8 with minor contributions from CYP3A4.{48275} Hydroxy pioglitazone binds to PPARγ (Ki = 1.2 μM) and activates PPARγ in a time-resolved FRET (TR-FRET) assay (EC50 = 2.1 μM).{48274}

• SKU: CAY28043-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 28043-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK