IAXO-102, CAS 1115270-63-7

Formulation: A solid

Formal Name: methyl 6-amino-6-deoxy-2,3-di-O-tetradecyl-α-D-glucopyranoside

Purity: ≥95%

Formula Markup: C35H71NO5

Formula Weight: 585,9

Shelf life (days): 1460

CAS Number: 1115270-63-7

Notes: IAXO-102 is a glycolipid and an antagonist of toll-like receptor 4 (TLR4).{17575} It inhibits lipid A-induced TLR4 activation in a cell-based assay (IC50 = 5.013 µM). IAXO-102 (10 mg/kg) reduces LPS-induced lethality in mice. It decreases angiotensin II-induced aortic expansion and rupture, as well as the incidence of abdominal aortic aneurysms, in ApoE-/- mice when administered at a dose of 3 mg/kg.{61728}

• SKU: CAY34567-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 34567-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK