ICA 110381, CAS 325457-99-6

Formulation: A solid

Formal Name: 4-chloro-N-(6-chloro-3-pyridinyl)-benzamide

Purity: ≥98%

Formula Markup: C12H8Cl2N2O

Formula Weight: 267,1

Shelf life (days): 1460

CAS Number: 325457-99-6

Notes: ICA 110381 is an activator of voltage-gated potassium channel Kv7.2.{39323} It induces rubidium efflux in an agonist-induced rubidium efflux assay using CHO cells (EC50 = 0.38 µM for the human channel). ICA 110381 also inhibits rubidium efflux from CHO cells expressing Kv7.1 (EC50 = 15 µM for the human channel). It reduces seizure number and increases the current threshold for seizure induction by amygdala-kindling in rats when administered at a dose of 30 mg/kg.{68544}

• SKU: CAY37294-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 37294-50
• Package Unit: 50 mg
• Quantity Unit: STK