Formulation: A crystalline solid
Formal Name: N-cyclopentyl-adenosine, 5′-nitrate
Purity: ≥95%
Formula Markup: C15H20N6O6
Formula Weight: 380,4
Shelf life (days): 1460
CAS Number: 871108-05-3
Notes: INNO-8875 is an adenosine A1 receptor agonist.{59827,59826} It binds to adenosine A1 receptors (Ki = 0.97 nM) and is greater than 10,000-fold selective for adenosine A1 over A2 receptors. Topical application of INNO-8875 (25 µg/eye) reduces intraocular pressure in a rabbit model of ocular hypertension.{59826} INNO-8875 (1-50 µg/kg) decreases atrial refractoriness and heart rate, as well as slows atrioventricular nodal conduction, in anesthetized rats.{59827}