Formulation: A neat oil
Formal Name: 2-chloro-2-(difluoromethoxy)-1,1,1-trifluoro-ethane
Purity: ≥98%
Formula Markup: C3H2ClF5O
Formula Weight: 184,5
Shelf life (days): 1460
CAS Number: 26675-46-7
Notes: Isoflurane is a halogenated ether with anesthetic properties.{37284} While the mechanism of isoflurane anesthesia is not fully understood, mice resistant to isoflurane anesthesia have an 86% decrease in gene expression for the GABAA receptor subunit β1 compared with isoflurane-sensitive mice, indicating that the GABAA receptor may be required for its anesthetic effect. In mice, isoflurane (1.5% for 4 hours) impairs spatial recognition memory in the spontaneous alternation test and Y-maze and increases levels of phosphorylated Jnk1/2 for at least 24 hours.{37283} Formulations containing isoflurane have been used as anesthetics.
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