Formulation: A solid
Formal Name: 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-avermectin A1a
Purity: ≥95%
Formula Markup: C47H72O14
Formula Weight: 861,1
Shelf life (days): 1460
CAS Number: 70209-81-3
Notes: Ivermectin B1b is the minor component (1a (>80%; Item No. 18768).{39419} It produces antiparasitic activity by binding to glutamate-gated chloride channels expressed on nematode neurons and pharyngeal muscle cells, inducing irreversible channel opening and very long-lasting hyperpolarization/depolarization of the neuron/muscle cell, thereby blocking further function.{30216,28250} Formulations containing ivermectin inhibit replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Vero/hSLAM cells.{55038}