Notes: KBP-066 is a dual amylin and calcitonin (CT) receptor agonist.{72495} It induces β-arrestin recruitment in cells expressing CT receptor subtype a or the amylin 3 receptor (AMY3) in a concentration-dependent manner. KBP-066 (50 µg/kg) reduces body weight and food intake in rats fed a high-fat diet. It prevents increases in fasting blood glucose levels in fa/fa Zucker diabetic fatty rats.