KIN1400, CAS 446826-86-4

Formulation: A solid

Formal Name: 7-[(2-benzothiazolylamino)[4-(difluoromethoxy)phenyl]methyl]-8-quinolinol

Purity: ≥98%

Formula Markup: C24H17F2N3O2S

Formula Weight: 449,5

Shelf life (days): 1460

CAS Number: 446826-86-4

Notes: KIN1400 is a small molecule activator of the RIG-1-like receptor (RLR) pathway that has antiviral activity.{41564} It induces expression of the innate immune genes RIG-1, MDA5, IFIT1, IFIT2, IFITM1, OAS3, and Mx1 in THP-1 cells stimulated with phorbol 12-myristate 13-acetate (PMA; Item No. 10008014). KIN1400 (20 μM) reduces West Nile and dengue viral RNA levels in HEK293 and Huh7 cells, respectively. It also inhibits hepatitis C virus (HCV) replication in a concentration-dependent manner in Huh7 cells.

• SKU: CAY22441-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 22441-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK