Formulation: A solid
Formal Name: 5-[(2,4-dioxo-5-thiazolidinyl)methyl]-2-methoxy-N-[[4-(trifluoromethyl)phenyl]methyl]-benzamide
Purity: ≥98%
Formula Markup: C20H17F3N2O4S
Formula Weight: 438,4
Shelf life (days): 1460
CAS Number: 213252-19-8
Notes: KRP 927 is a thiazolidinedione dual agonist of PPARα and PPARγ (EC50s = 149 and 83 nM, respectively, in transactivation assays).{59890} It decreases hyperglycemia and hyperinsulinemia in ob/ob mice in a dose-dependent manner. KRP 927 (10 or 30 mg/kg) reduces serum total cholesterol and triglyceride levels in hamsters.