Formulation: A crystalline solid
Formal Name: 3-hydroxy-α-methyl-L-tyrosine
Purity: ≥98%
Formula Markup: C10H13NO4
Formula Weight: 211,2
Shelf life (days): 1460
CAS Number: 555-30-6
Notes: L-(−)-α-Methyldopa is a dopamine (DOPA) decarboxylase inhibitor (ED50 = 21.8 mg/kg) and has antihypertensive activity in vitro and in vivo.{36001,36002,36000} L-(−)-α-Methyldopa enters the CNS and is metabolized to form α-methylnorepinephrine which acts as an agonist at α2-adrenergic receptors.{36001,36000} Formulations containing L-(−)-α-methyldopa are used to lower blood pressure.{36002} L-(−)-α-Methyldopa also improves trophoblast and endothelial cellular interactions in vitro.{36001}