Larixyl Acetate, CAS 4608-49-5

Formulation: A solid

Formal Name: (αS,1S,4S,4aS,8aR)-4-(acetyloxy)-α-ethenyldecahydro-α,5,5,8a-tetramethyl-2-methylene-1-naphthalenepropanol

Purity: ≥98%

Formula Markup: C22H36O3

Formula Weight: 348,5

Shelf life (days): 1460

CAS Number: 4608-49-5

Notes: Larixyl acetate is a diterpenoid that has been found in Larix and has transient receptor potential canonical 6 (TRPC6) inhibitory and analgesic activities.{65138,65139} It inhibits the activity of TRPC6 (IC50 = 0.58 µM) and is selective for TRPC6 over TRPC3 (IC50 = 6.83 µM), as well as over nine additional TRP channels at 10 µM.{65138} Intrathecal administration of larixyl acetate reduces mechanical and cold allodynia in a rat model of neuropathic pain induced by spared nerve injury (SNI).

• SKU: CAY35309-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 35309-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK
• Application: Reinstoffe