LIH383 (trifluoroacetate salt)

Formulation: A solid

Formal Name: (S)-6-amino-2-((2S,5S,8S,11S,20S)-20-amino-11-benzyl-2,5-bis(3-guanidinopropyl)-8-(2-(methylthio)ethyl)-4,7,10,13,16,19-hexaoxo-21-phenyl-3,6,9,12,15,18-hexaazahenicosanamido)hexanamide, trifluoroacetate salt

Purity: ≥98%

Formula Markup: C45H72N16O8S • XCF3COOH

Formula Weight: 997,2

Shelf life (days): 1460

Notes: LIH383 is a peptide agonist of chemokine (C-X-C motif) receptor 7 (CXCR7), a chemokine and opioid peptide scavenger receptor.{67538} It selectively activates CXCR7 (EC50 = 0.61 nM) over μ-, δ-, and κ-opioid receptors and the nociceptin opioid peptide (NOP) receptor in β-arrestin recruitment assays at 3 µM. LIH383 (3 µM) prevents CXCR7 uptake of opioid peptides induced by the non-selective opioid receptor agonist dynorphin A (Item No. 18169) in U87-ACKR3 cells.

• SKU: CAY36967-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 36967-25
• Package Unit: 25 mg
• Quantity Unit: STK