Formulation: A solid
Formal Name: 5-oxo-L-prolyl-L-glutaminyl-L-tryptophyl-L-alanyl-L-valylglycyl-L-histidyl-L-phenylalanyl-L-methioninamide, trifluoroacetate salt
Purity: ≥98%
Formula Markup: C51H68N14O11S • XCF3COOH
Formula Weight: 1085,2
Shelf life (days): 1460
Notes: Litorin is a peptide originally isolated from L. aurea that has diverse biological activities.{64048,64049,64050,64051} It is an agonist of the gastrin-releasing peptide receptor (GRPR) and the neuromedin B (NMB) receptor in BALB/c 3T3 fibroblasts expressing the human receptors (EC50s = 0.44 and 0.03 nM, respectively) and binds to frog bombesin receptor subtype 4 (BB4) in CHO-K1 cells (Ki = 1.2 nM).{64049,64050} Litorin (10-100 ng/kg) induces contractions of isolated guinea pig gallbladder.{64051} It decreases food intake in rats when administered at doses ranging from 4 to 128 µg/kg.{64048}
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